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安定是临床应用最广泛的一种抗焦虑药,它因疗效高、毒性低、价廉等而深受患者欢迎,且大有取代利眠宁之趋势,但如滥用、过量服用或长期使用,尤其是与其他镇静催眠药并用时,也会引致一系列不良反应和依赖性,甚至产生停药综合征。为此,我们在建立利眠宁血浓度测定之后,又于最近完成了紫外法测定安定血浓度的方法,为临床更合理、安全地使用安定提供较可靠的依据。
Diazepam is the most widely used anti-anxiety medicine in clinic. It is welcomed by patients due to its high curative effect, low toxicity, low cost and so on. It greatly replaces the trend of Chlordiazepoxide, but if abuse, overdose or long-term use, Especially when used in combination with other sedatives and hypnotics, it can cause a series of adverse reactions and dependencies, even resulting in withdrawal syndrome. For this reason, we established the method of measuring the concentration of diazepam after UV determination of Limomine blood concentration in recent years to provide a more reliable basis for the more rational and safe use of diazepam.