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目的 探讨 5 0岁以上绝经妇女发生卵巢肿瘤的临床病理学原因。方法 对 1998年 1月至 2 0 0 2年 7月发生的 136例 5 0岁以上绝经妇女卵巢肿瘤患者的临床资料及病理结果进行回顾性分析。结果 136例中恶性卵巢肿瘤 5 9例 (43 4 % ) ,交界性肿瘤 6例 (4 4 % ) ,良性卵巢肿瘤 71例 (5 2 2 % )。恶性卵巢肿瘤以 6 0～ <6 5岁发生率最高 (48 5 % ) ,70岁以上发生率较低 (2 0 0 %～ 2 6 7% ) (P <0 0 5 )。在病理组织切片上 ,良性卵巢肿瘤以黏液性囊腺瘤为多 ,恶性卵巢肿瘤以浆液性囊腺癌为多。对 10 8例患者用彩色超声检查测量的肿瘤直径进行分析 ,其中以肿瘤直径 >10cm组恶性卵巢肿瘤发生率最高 ,与直径 <5cm组比较差异有显著性意义 (P <0 0 5 )。结论 绝经后应定期进行常规妇科检查和宫颈刮片细胞学检查 ,如有异常宜及时进行影像检查及肿瘤标志物和病理检查 ,积极地进行治疗。
Objective To investigate the clinicopathologic causes of ovarian tumors in over 50 years old menopausal women. Methods A retrospective analysis was performed on the clinical data and pathological findings of 136 cases of ovarian cancer in menopausal women over the age of 50 from January 1998 to July 2002. Results Of the 136 cases, 59 (43.4%) had malignant ovarian tumors, 6 (44%) had borderline tumors and 71 (52.2%) had benign ovarian tumors. Malignant ovarian tumors had the highest incidence (60.5%) at 6 ~ 6 years and lower incidence (70% ~ 267%) over 70 years (P <0.05). Pathological tissue sections, benign ovarian tumors to mucinous cystadenoma as more malignant ovarian tumors to serous cystadenocarcinoma. The diameter of tumors detected by color sonography in 108 patients was analyzed. The highest incidence of malignant ovarian tumors was found in tumors> 10cm in diameter, and the difference was statistically significant (P <0.05). Conclusions Postmenopausal women should take regular gynecological examinations and cervical smear cytology tests in regular postmenopausal period. In case of abnormalities, they should timely conduct imaging examination, tumor markers and pathological examination, and actively treat them.