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本文测定了74例新生儿肺炎患儿血中SOD活性、LPO和VE浓度并与32例足月正常新生儿做比较.结果显示：SOD活性在急性期显著降低，恢复期虽有回升，但仍未达到正常水平。LPO浓度在急性期显著高于恢复期和正常对照组，以重症者更明显。VE浓度在急性期显著1低于正常对照组。34例患儿急性期和恢复期的自身对照结果，三项指标在两期之间均有显著性差异。结果表明自由基脂质过氧化损伤机制参与或加重了肺炎的病理过程。
In this paper, 74 cases of neonatal pneumonia in children with serum SOD activity, LPO and VE concentrations and with 32 cases of full-term normal newborns were compared.The results showed that: SOD activity decreased significantly in the acute phase, although recovery recovered, but still Did not reach the normal level. LPO concentration in the acute phase was significantly higher than the recovery and the normal control group, with severe cases were more obvious. VE concentration in the acute phase was significantly lower than the normal control group. 34 cases of children with acute and convalescent self-control results, the three indicators were significantly different between the two periods. The results showed that free radical lipid peroxidation injury mechanism involved in or aggravate the pathological process of pneumonia.