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Rock creep properties can be used to predict the long-term stability in rock engineering. In reservoir bank slopes, sandstones which are frequently used in the bank slope undergoing long-term effects of dry-wet (DW) cycles due to periodic water inundation and drainage may gradually accumulate creep deformation, resulting in rock structure's damage or even geological hazards such as landslides. To fully investigate the effect of DW cycles on the creep damage properties of sandstone, triaxial creep tests were conducted on saturated sandstone with different DW cycles by using a triaxial rheometer apparatus. The experimental results show that both the instantaneous strain and the stabilized strain increase with the DW cycles. In addition, using the Burgers model, four kinds of functions including an exponentially decreasing function, a linearly decreasing function, a linearly increasing function and an exponentially increasing function were proposed to express the relationships between the shear modulus, viscoelastic parameters of the Burgers model and the deviatoric stress under different DW cycles. Through comparative analysis, it is found that the theoretical curves generated using proposed four kinds of functions are in good agreement with the experimental data. Furthermore, macromorphological and microstructural observations were performed on specimens after various triaxial rheological tests. For samples with small number of DW cycles,approximately X-shaped fracture surfaces were observed in shear failure zones, whereas several shear fractures including obvious axial and horizontal tensile cracks, and flaws were found for samples with relatively large DW cycles due to long-term propagation and evolution of micro-fissures and micro-pores. Furthermore, as the DW cycles increases,the variation in micro-structure of samples after creep failure was summarized into three stages, namely, a stage with good and dense structure, a stage with pore and fissure propagation, and a stage with extensive increase of pores, fissures and loose particles. It is concluded that the combination effect of permeation of water molecules through pores and fissures within sandstone, and the propagation of preexisting pores and fissures owing to the dissolution of mineral particles leads to further deterioration of the mechanical properties of sandstone as the number of DW cycles increases. This study provides a fundamental basis for evaluating the long-term stability of reservoir bank slopes under cyclic fluctuations of water level.