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目的 分析广东省首例传染性非典型肺炎病例 (SARS)的流行病学特征 ,为追溯传染源提供科学依据。方法 采用统一的个案调查表对广东省SARS首发病例进行调查 ,同时对其密切接触者进行流行病学调查 ,分析首发病例流行病学特征、续发病例情况及各市首发病例之间的联系。结果 2 0 0 2年 11月 16日至 2 0 0 3年 4月 16日 ,广东省有 13个地级市报告发生SARS(依次为佛山、河源、中山、江门、广州、深圳、肇庆、东莞、汕头、惠州、汕尾、湛江、韶关等市 )。对 13个市的首发病例进行分析 :13例首发病例中 ,厨师和干部各有 3例 ,农民、退休人员、工人各 2例、商业人员 1例 ;男女比为 1∶0 .6 ,年龄在 18～ 84岁之间 ,30～ 5 0岁组占 77% (10 /13) ;死亡 4例。 2 0 0 0年 11月至 2 0 0 3年 1月期间 ,7个市报告的首发病例中 ,6例为本市感染病例 ,1例怀疑为从广州输入病例 ,均无明确同类病例接触史 ,其中有 6例引起二代或三代病例 ;2 0 0 3年 2月无新发病市 ;2 0 0 3年 3月～ 4月 16日 ,6市报告新发病例 ,2例为本市感染发病 ,3例感染地为香港、1例感染地为广州 ,5例有明确的同类病例密切接触史 ,只有 2例引起第二代病例。结论 未发现 13例首发病例间存在相互传播的线索。从13个市追溯到的可能传染源集中在珠江三角
Objective To analyze the epidemiological characteristics of the first case of SARS in Guangdong Province and provide a scientific basis for tracing the source of infection. Methods A case-by-case survey was conducted to investigate the first SARS cases in Guangdong Province. At the same time, epidemiological investigation of SARS patients in close contacts was conducted. The epidemiological characteristics of the first cases, the incidence of recurrence and the association between the first SARS cases in each city were analyzed. Results From November 16, 2002 to April 16, 2003, 13 prefecture-level cities in Guangdong reported SARS (followed by Foshan, Heyuan, Zhongshan, Jiangmen, Guangzhou, Shenzhen, Zhaoqing, Dongguan , Shantou, Huizhou, Shanwei, Zhanjiang, Shaoguan and other cities). The first case of 13 cities was analyzed: 13 cases of first case, 3 cases of chef and cadre, 2 cases of peasants, retirees and workers, 1 case of commercial staff, 1:06 male-to-female ratio, Between 18 and 84 years old, 77% (10/13) were in 30 ~ 50 years old group; 4 died. Between November 2000 and January 2003, of the seven first reported cases in the seven municipalities, 6 were city-based and 1 were suspected of being imported from Guangzhou. There was no clear history of similar cases , Of which 6 cases caused the second or third generation of cases; no new onset in February 2003; March 2003 ~ April 16, 6 new cases reported in 6 cities, 2 cases of infection in the city The incidence of infection was 3 in Hong Kong, 1 in Guangzhou, 5 in a clear history of close contact with similar cases, and only 2 in the second generation of cases. Conclusion No clues were found among 13 cases of first transmission. The possible sources of infection dating back to 13 cities are concentrated in the Pearl River Delta