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目的:探讨外周血红细胞分布宽度(RDW)变化与急性心肌梗死(AMI)患者临床预后的关系。方法:以2012年1月-2014年1月我科收治的AMI患者162例为研究组,同期体检健康者80例为对照组,比较两组RDW及其与AMI临床预后的关系。结果:研究组RDW的水平明显高于对照组[(14.04±1.22)%vs(13.27±1.12)%,P<0.05]。研究组中死亡组的RDW水平显著高于存活组[(15.58±1.59)%,vs(13.41±1.00)%,P<0.05];研究组中RDW增高组91例与正常组71例的病死率无明显差异(P>0.05),而RDW增高组患者心力衰竭、恶性心律失常及再发心肌梗死发生率分别43.96%、38.46%和24.18%,均显著高于RDW值正常组的15.49%、11.27%和7.04%(P<0.05)。结论:AMI患者的RDW水平高于健康人,且RDW水平与临床预后具有一定相关性。
Objective: To investigate the relationship between the distribution of peripheral blood red blood cells (RDW) and the clinical prognosis of patients with acute myocardial infarction (AMI). Methods: A total of 162 AMI patients admitted to our department from January 2012 to January 2014 were selected as research group. 80 healthy subjects were selected as control group. The relationship between RDW and the clinical prognosis of AMI was compared between the two groups. Results: The level of RDW in the study group was significantly higher than that in the control group [(14.04 ± 1.22)% vs (13.27 ± 1.12)%, P <0.05]. The RDW level in the death group was significantly higher than that in the survival group [(15.58 ± 1.59)% vs (13.41 ± 1.00)%, P <0.05]. In the study group, the mortality of 91 patients in the RDW increased group and 71 in the normal group (P> 0.05). The incidence of heart failure, malignant arrhythmia and recurrent myocardial infarction were 43.96%, 38.46% and 24.18% respectively in the RDW high group, which were significantly higher than those in the RDW normal group (15.49%, 11.27) % And 7.04% (P <0.05). Conclusions: The RDW level in patients with AMI is higher than that in healthy people, and the RDW level has a certain correlation with clinical prognosis.