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目的:探讨笑气(氧化亚氮)联合米索前列醇在不孕症患者宫腔镜输卵管插管通液术中的镇痛效果。方法:将100例需要作宫腔镜输卵管插管通液的不孕症患者随机分为笑气联合米索前列醇组(研究组)、米索前列醇组(对照组)。观察两组镇痛效果,术前术后血压、脉搏,宫颈扩张情况、离院时间及有无不良反应。结果:研究组镇痛有效率100%,完全无痛达70%,而对照组镇痛有效率只有48%,完全无痛只有8%,两组比较差异有统计学意义(P<0.01);研究组术中能保持循环功能稳定。结论:笑气联合米索前列醇用于不孕症患者宫腔镜输卵管通液术中镇痛,效果十分良好,值得临床推广应用。
Objective: To investigate the analgesic effect of nitrous oxide combined with misoprostol in hysteroscopic tubal catheterization in patients with infertility. Methods: 100 infertility patients who needed hysteroscopic tubal catheterization were randomly divided into noxious misoprostol group (study group) and misoprostol group (control group). The analgesic effects, preoperative and postoperative blood pressure, pulse, cervical dilatation, time to hospital and adverse reactions were observed. Results: In the study group, the effective rate of analgesia was 100% and the rate of painlessness was 70%. While in the control group, the analgesic effective rate was only 48% and the painless rate was only 8%. There was significant difference between the two groups (P <0.01). Study group can maintain circulatory function and stability. Conclusion: Noxious gas combined with misoprostol is an effective analgesic for hysteroscopic tubal fluid in patients with infertility. The effect is very good and worthy of clinical application.