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为观察不同年龄Ｗｉｓｔａｒ大鼠一侧睾丸切除后，另侧案丸的代偿性反应（ＣＴＡ），通过光镜、电镀和显微图像分析其代偿睾丸的组织学变化特征，采用放免法测定血清性激素浓度，以期揭示不同年龄睾丸受损后代偿反应的变化规律。结果：仅１０、２０天龄大鼠的另侧睾丸重量、体积较对照有明显增大（Ｐ＜０．０１），生精细胞和非生精细胞均出现肥大、增生，且细胞超微结构有退化变性改变。血清ＦＳＨ高低与ＣＴＡ明显相关。本研究表明：实验鼠在一侧睾丸受损后，另侧睾丸将发生ＣＴＡ，且年龄越小越显著，而性成熟鼠的睾丸将不出现ＣＴＡ。年龄是影响ＣＴＡ的重要因素之一。
To observe the different age Wistar rat side of orchidectomy, the other side of the case of compensatory response (CTA), by light microscopy, electroporation and microscopic images of the compensatory testis histological changes were measured by radioimmunoassay Serum levels of sex hormones in order to reveal changes in compensatory response after testicular damage at different ages. Results: The weight and volume of the other testis in 10 and 20 days old rats were significantly increased compared with the control (P <0.01). Both spermatogenic cells and non-germ cells showed hypertrophy and hyperplasia, and ultrastructure of cells Degenerative degeneration has changed. The level of serum FSH was significantly correlated with CTA. This study shows that: Experimental rats on one side of the testes damaged, the other side of the testis will occur CTA, and the younger the more significant, while the sexual maturity of the testis will not appear CTA. Age is one of the important factors affecting CTA.