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伊康唑是一种新的广谱。强效口服抗真菌药。我们应用伊康唑胶囊,以每天100mg的剂量治疗皮肤癣菌病患者120例,随访观察113例,分为A(30天)及B(15天)两组,结果两均有明显效果,但对手足癣的治疗,A组的治愈率明显高于B组,两者经统计学处理P<0.001,有非常显著的差异,说明对手、足癣的治疗以30天为一疗程较为合适;体、股癣的治愈率B组为81.25％,有效率为100％。可见对体、股癣的治疗一般15天可治愈,对少数较广泛病例继续治疗1～2周亦可达到治愈目的。 伊康唑(Itracouazole,R51211)是比利时杨森公司研制的一种新的口服抗真菌药。从1982年以来已于欧洲、美洲、非洲、澳洲等27个国家应用40万胶囊(50mg)进行临床验证,表明对浅部真菌病及系统性真菌病均有明显效果,但在我国尚无临床应用的报告,我们于1987年12月～1988年6月应用2700胶囊(100mg)对120例皮肤癣菌病患者进行临床治疗观察,获得满意效果,兹报告如下。
Iaconazole is a new broad spectrum. Potent oral antifungal. We use the Iconazole capsules daily dose of 100mg dermatophytosis patients treated 120 cases, followed up 113 cases were observed, divided into A (30 days) and B (15 days) two groups, the results were both significant effect, but The treatment of hand, foot and ringworm, the cure rate of group A was significantly higher than that of group B, both of which were statistically significant (P <0.001). There was a very significant difference, indicating that the treatment of rival and tinea pedis was suitable for 30 days. , The cure rate of jock itch in group B was 81.25%, the effective rate was 100%. Can be seen on the body, the treatment of jock itch generally 15 days can be cured, for a few more cases continue treatment for 1 to 2 weeks can be cured. Itracouazole (R51211) is a new oral antifungal agent developed by Janssen AG in Belgium. Since 1982, 40 million capsules (50mg) have been used in 27 countries in Europe, the Americas, Africa and Australia for clinical validation, indicating that they have obvious effects on superficial fungal diseases and systemic fungal diseases. However, in our country there is no clinical Application report, we in December 1987 ~ June 1988 2700 capsules (100mg) 120 cases of dermatophytosis in patients with clinical observation and satisfactory results, it is reported as follows.