论文部分内容阅读
目的 :探讨通脉口服液对慢性肾炎血液流变学的影响。方法 :建立大鼠系膜增殖性肾炎模型 ,随机分为通脉高剂量组、通脉低剂量组、金水宝组、病理模型组及正常对照组 ,治疗 4周后 ,眼眶采血 ,对血液流变学指标进行测定。结果 :通脉口服液可以改善系膜增殖性肾炎大鼠全血比粘度 (包括低切及高切 )、聚集指数、血浆比粘度、红细胞压积 (P均 <0 .0 1)及全血还原粘度 (P <0 .0 5 )。结论 :通脉口服液有降低全血比粘度 (包括低切及高切 )、聚集指数、血浆比粘度、红细胞压积 (P均 <0 .0 1)及全血还原粘度 (P <0 .0 5 )的作用 ,可以改善血液流变学。
Objective: To investigate the effect of Tongmai Oral Liquid on hemorheology of chronic nephritis. METHODS: A rat model of mesangial proliferative nephritis was established and randomly divided into Tongmai high-dose group, Tongmai low-dose group, Jinshuibao group, pathological model group, and normal control group. After 4 weeks of treatment, the eyelids were collected for blood flow. The index of change is measured. RESULTS: Tongmai Oral Liquid can improve the specific viscosity of whole blood (including low-cut and high-cut), aggregation index, specific viscosity of plasma, hematocrit (P <0.01) and whole blood in rats with mesangial proliferative nephritis. Reduced viscosity (P < 0.05). CONCLUSION: Tongmai Oral Liquid has the effects of lowering the specific viscosity of whole blood (including low-cut and high-cut), aggregation index, specific viscosity of plasma, hematocrit (P<0.01), and reduced viscosity of whole blood (P<0. The effect of 0 5) can improve blood rheology.