【摘 要】
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It is important to assess myocardial perfusion in the diagnosis, treatment and risk stratification of patients with coronary artery disease. At present, single-
【机 构】
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Department of Cardiology
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It is important to assess myocardial perfusion in the diagnosis, treatment and risk stratification of patients with coronary artery disease. At present, single-photon emission computed tomography (SPECT) is used to evaluate myocardial perfusion, but it is limited by relatively low spatial resolution, the need to inject radioisotopes, and not being able to be performed at the patient s bedside. Using intracoronary injection of ultrasound contrast agent, the potential of myocardial contrast echocardiography (MCE) instead of perfusion assessment has been proved in numerous animal and human studies. Recent improvements in contrast agents have resulted in stable microbubbles that, following intravenous administration, traverse the pulmonary circulation and reach the left heart. Combined with the emergence of contrast-specific imaging modalities along with quantitative analytical method, intravenous MCE is now a feasible and promising noninvasive technique for perfusion assessment.
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