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近十年来,由于癌基因的深入研究,使人们对癌变原理及癌恶性行为有逐步深入的了解。癌基因是正常细胞生长和分泌不可缺少的基因,但一旦被外源性因素(化学、物理、病毒等致癌因素)激活,使表达在基因产物的质和量发生改变,失去原有调节系统对它的调控,产生异常和体质性的表达,就易使正常细胞转化为癌细胞。一般正常细胞需积累多次突变才能成为癌细胞。有关卵巢癌主要癌基因和抑癌基因研究概况介绍
In the past ten years, due to the in-depth study of oncogenes, people have got a deep understanding of the principle of canceration and the malignant behavior of cancer. Oncogene is an indispensable gene for normal cell growth and secretion. However, once activated by exogenous factors (such as chemical, physical, viral and other oncogenic factors), the expression and quality of the gene product are changed, and the original regulatory system is lost Its regulation, resulting in abnormal and constitutional expression, easy to make normal cells into cancer cells. Normal cells need to accumulate multiple mutations in order to become cancer cells. About ovarian cancer major oncogene and tumor suppressor gene research overview