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目的明确广元市企事业行政单位职员脂肪肝的患病率及相关危险因素。方法2005年1月~2006年12月在我院体检的企事业行政单位职员。体检内容涉及问卷调查、体格检查、血脂检测、空腹血糖、肝功能及肝脏实时超声检查。结果有4 504人完成调查,约占广元行政企事业单位职员人数的12.08%(4 504/37 267)(以2006年统计局人事年报为准),男2 689人,平均(44.49±14.03)岁;女1 815人,平均(39.52±11.93)岁。B超共检出脂肪肝194例,占4.31%,其中酒精性脂肪肝占4.22%,非酒精性脂肪肝占95.78%。无论是男性还是女性,脂肪肝患病率随年龄增长而增加,60岁前达到高峰,随后稍有下降;男性脂肪肝患病率显著高于女性(χ2=65.648,P<0.001),而60岁后男女间脂肪肝患病率无差异(χ2=1.368,P=0.242)。脂肪肝组性别、年龄、超重、血压、血脂、血糖等因素均显著高于对照组(P<0.05)。多元回归分析显示:体重指数(BMI)、超重、文化程度、性格特点、夜间加餐、甜食与脂肪肝密切相关,尤其超重可增加脂肪肝的患病风险。同时运动量少、不良饮食习惯、生活无规律也是脂肪肝患病的风险因素,而过量饮酒并不是脂肪肝患病风险的高危因素。结论广元市行政企事业单位职员脂肪肝患病率较高,主要是非酒精性脂肪肝、超重及饮食行为习惯不良与脂肪肝发病相关。
Objective To determine the prevalence of fatty liver and its related risk factors among staff in administrative units in Guangyuan. Methods January 2005 ~ December 2006 in our hospital physical examination of staff in administrative units. Physical examination involves questionnaires, physical examination, blood lipids, fasting blood glucose, liver function and real-time liver ultrasound. As a result, 4 504 people completed the survey, accounting for 12.08% (4 504/37 267) of the total number of administrative staff and workers of Guangyuan (based on 2006 Annual Bureau of Statistics), 2 689 males, with an average of (44.49 ± 14.03) Years old; female 1 815 people, average (39.52 ± 11.93) years old. B-total detected 194 cases of fatty liver, accounting for 4.31%, of which 4.22% alcoholic fatty liver, non-alcoholic fatty liver accounted for 95.78%. The prevalence of fatty liver increased with age and peaked at age 60 before declining slightly in both males and females. The prevalence of fatty liver in males was significantly higher than that of females (χ2 = 65.648, P <0.001) There was no difference in the prevalence of fatty liver between men and women (χ2 = 1.368, P = 0.242). Fatty liver group sex, age, overweight, blood pressure, blood lipids, blood glucose and other factors were significantly higher than the control group (P <0.05). Multiple regression analysis showed that body mass index (BMI), overweight, educational level, personality traits, evening meal, sweets and fatty liver are closely related, especially overweight can increase the risk of fatty liver. At the same time less exercise, poor eating habits, irregular life is also a risk factor for fatty liver disease, and excessive drinking is not a risk factor for fatty liver risk. Conclusions The prevalence of fatty liver in staffs of administrative enterprises and public institutions in Guangyuan City is high, mainly non-alcoholic fatty liver disease. The overweight and poor dietary habits are associated with the incidence of fatty liver.