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作者在英国伦敦皇家免费医院内科用人类淋巴母细胞干扰素治疗3例因静脉输注免疫球蛋白所致的慢性非甲非乙型病毒性肝炎患者。其中2例于治疗前肝功能异常达2年以上。另1例病程4个月以上。3例患者均呈低丙种球蛋白血症,IgG 低于1.5g/L,IgA和 IgM 低于0.1g/L。研究期间,每2周静脉输注丙种球蛋白1次200mg/kg。肌注人类淋巴母细胞干扰素每周3次,维持时改为每周2次。例1每周用1000万 U,疗程2个月,只用1个疗程。例2每周用500~
The authors treated three patients with chronic non-A, non-B hepatitis caused by intravenous immunoglobulin with human lymphoblastoid interferon in the Royal Free Hospital of London, England. Two of them had abnormal liver function for more than 2 years before treatment. Another case of more than 4 months duration. All 3 patients showed hypogammaglobulinemia with IgG less than 1.5 g / L and IgA and IgM less than 0.1 g / L. During the study, intravenous gamma globulin was administered 200 mg / kg intravenously every 2 weeks. Intramuscular injection of human lymphoblastoid interferon 3 times per week, maintenance time to 2 times a week. Example 1 10 million U per week, treatment 2 months, only 1 course of treatment. Example 2 weekly use 500 ~