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目的 本研究目的在于探讨剖胸术后美施康定片剂的镇痛疗效并与度冷丁针剂进行比较。方法 2 0 0例病人随机分为A、B两组 ,A组口服或直肠给予美施康定片 ,成人每次 3 0mg ,儿童 0 .4mg/kg/次 ,间隔 12小时 ,即每日 2次 ,连续 5天 ;B组肌注度冷丁 ,成人每次 5 0～ 75mg ,儿童 1mg/kg/次 ,每日 3～ 6次不等 ,连续 5天。结果 A组与B组均具有确切的镇痛效果 ,两组比较无统计学差异 (P >0 .0 5 ) ,而A组的副作用较B组低 ,两组比较有显著性差异 (P <0 .0 5 )。结论 在剖胸术后镇痛方面美施康定片可作为一种首选药 ,值得临床推广使用。
Objectives The purpose of this study was to investigate the analgesic efficacy of Meishi Kangding tablets after thoracotomy and to compare with that of pethidine. Methods A total of 200 patients were randomly divided into A and B groups. Group A received meclizine orally or rectally at a dose of 30 mg / kg for adults and 0 .4 mg / kg for children at intervals of 12 hours, ie twice a day , For 5 consecutive days; Group B intramuscular injection of cold, adult each 50 ~ 75mg, children 1mg / kg / time, 3 to 6 times a day for 5 days. Results Both group A and group B had the exact analgesic effect. There was no significant difference between the two groups (P> 0.05), but the side effects in group A were lower than those in group B (P < 0 .0 5). Conclusion In the aspect of postoperative thoracotomy, Meishenkang tablets can be used as a preferred drug and is worthy of clinical promotion.