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回顾性分析了自１９８０～１９８９年来接受手术治疗的７４２例大肠腺癌病例。通过对临床病理指标的单因素和多因素Ｃｏｘ回归分析，研究影响大肠癌患者预后的独立性因素。研究结果表明：淋巴结受累（β＝０．４９８２，Ｐ＜０．０００１）及肠壁浸润深度（β＝０．１２６５，Ｐ＜０．０３１２）是影响大肠癌预后的独立性指标。由此提示：Ｄｕｋｅｓ′分期（β＝０．６３３４，Ｐ＜０．０００１）是一项独立的预后指标，亦是判断大肠癌患者临床结局的最重要和最准确的依据。
We retrospectively analyzed 742 cases of colorectal adenocarcinoma undergoing surgical treatment from 1980 to 1989. Univariate and multivariate Cox regression analysis of clinical pathological indicators was used to study the independent factors affecting the prognosis of patients with colorectal cancer. The results showed that lymph node involvement (β = 0.4982, P <0.0001) and depth of intestinal infiltration (β = 0.1265, P <0.0312) were independent indicators of the prognosis of colorectal cancer. This suggests that the Dukes’ stage (β = 0.6334, P <0.0001) is an independent prognostic indicator and is the most important and accurate basis for judging the clinical outcome of patients with colorectal cancer.