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骨髓移植是将恶性血液病或克隆性疾病的患者自身的骨髓组织摧毁,植入同基因或异基因的正常骨髓以代替自身原有疾病的骨髓,使造血及免疫功能重建。骨髓移植须通过1.经典方法是受者接受强烈化疗为环磷酰胺60 mg/kg,共4天,移植前1日加用全身放射治疗约600～1200 cGy,目的抑制患者免疫功能及摧毁有病的骨髓细胞,从而允许外来的移植物植入。2.植入白细胞抗原(HLA)相同的供者骨髓,约含有核细胞1×10~3/kg,其中含有造血干细胞。约经
Bone marrow transplantation is to destroy the bone marrow tissue of patients with hematologic malignancies or clonal diseases and implant normal or allogeneic normal bone marrow instead of the bone marrow of the original disease to reconstruct hematopoietic and immune functions. Bone marrow transplantation should pass 1. The classic method is to receive intensive chemotherapy for cyclophosphamide 60 mg / kg for 4 days, plus systemic radiotherapy on the 1st day before transplantation about 600 ~ 1200 cGy, the purpose of inhibiting the patient’s immune function and destroy Diseased bone marrow cells, allowing for the implantation of foreign grafts. Implantation of leukocyte antigen (HLA) The same donor bone marrow, containing about 1 × 10 ~ 3 / kg of nucleated cells, which contain hematopoietic stem cells. About the day