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难辨梭状芽胞杆菌(CD)腹泻主要是一种医院内疾病。据记载,在住院(特别是长期住院)患者中CD定居率在20％以上,而健康成人中不常见。虽然接触抗生素及进入医院是CD腹泻的危险因素,但关于其后引起疾病发生及无症状粪便排菌的作用了解甚少。为阐明CD感染的自然史,作者对该院长期住院的患者进行了前瞻性研究。研究对象为3个病区中住院7天以上的患者。这3个病区是根据过去CD腹泻发病率不同而确定,即发病率较高的外科,发病率
Diarrhea of Clostridium difficile (CD) is primarily a hospital disease. It has been documented that the CD settlement rate is above 20% in hospitalized patients (especially long-term hospital stays), which is uncommon in healthy adults. Although exposure to antibiotics and admission to hospitals is a risk factor for CD diarrhea, little is known about the subsequent role of disease causing and asymptomatic excretion of feces. To clarify the natural history of CD infection, the authors conducted a prospective study of patients hospitalized for long-term hospitalization. Subjects were hospitalized in 3 ward for more than 7 days. The three wards are based on the past CD diarrhea morbidity is different, that is, the incidence of higher surgical, the incidence