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咖啡因可诱发哺乳动物(包括人)离体细胞染色体畸变巳被遗传学家所公认。至于其是否引起哺乳动物体内细胞染色体畸变,国外尚有不同看法。Nemiyovskii和Kuklmann等认为它可诱导体内染色体发生
Caffeine-Induced Chromosome Aberrations in Ex Vivo Cells in Mammals, Including People, have been recognized by geneticists. As to whether it causes chromosome aberrations in mammalian cells, there are different views abroad. Nemiyovskii and Kuklmann so that it can induce chromosome formation in vivo