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目的：分析严重急性呼吸综合征(SARS)患者的临床特点。方法：回顾性分析56例家庭聚集发病SARS患者的临床资料。结果：SARS病情轻重分型无性别差异,60岁及以上患者、有慢性病史患者预后较差。其主要症状为发热、咳嗽、气短、胸闷、乏力、呼吸困难等；再次发热、呼吸困难以及LDH、CK-MB、HBDH、血糖、BUN、Cre升高、K、T细胞亚群、SaO_2、SpO_2降低与预后相关；X线胸片显示的肺病变、肺叶受损、肺受损面积更大,病情严重。SARS可伴有多种并发症,尤其合并有ARDS、休克、肾衰、多脏器衰竭者病死率明显增高。结论：SARS以呼吸道症状为主,淋巴细胞计数、T细胞亚群、血气分析、X线胸片等均有一定的改变,且以并发ARDS、休克及多脏器衰竭者病死率明显增高。
Objective: To analyze the clinical features of patients with severe acute respiratory syndrome (SARS). Methods: The clinical data of 56 SARS patients with family aggregation were retrospectively analyzed. Results: There was no gender difference in the severity of severe acute respiratory syndrome (SARS). Patients with chronic diseases history of 60 years old and older had poorer prognosis. The main symptoms are fever, cough, shortness of breath, chest tightness, weakness, dyspnea, etc .; reheat, dyspnea and increase of LDH, CK-MB, HBDH, blood glucose, BUN, Cre, K, T cell subsets, SaO_2, SpO_2 Reduce the prognosis; X-ray showed lung lesions, lung damage, lung damage larger, serious condition. SARS can be associated with a variety of complications, especially with ARDS, shock, renal failure, multiple organ failure mortality was significantly higher. Conclusion: SARS is mainly characterized by respiratory symptoms. Lymphocyte counts, T cell subsets, blood gas analysis, X-ray and so on are all changed. The mortality of SARS patients complicated by ARDS, shock and multiple organ failure is significantly higher.