论文部分内容阅读
目的:研究控制性超促排卵下卵巢低反应的预测指标及妊娠结局情况。方法:选择拟行IVF/ICSI助孕治疗的152名不孕症女性,根据卵巢反应性分为两组:低反应组(获卵数<4个)、非低反应组(获卵数≥4个)。收集不孕症女性的相关临床资料进行分析。结果:卵巢低反应的发生率为18.42%(28/152)。两组中年龄、基础FSH值、FSH/LH值、AFC有显著性差异。多因素Logistic回归分析显示:年龄和AFC进入回归模型,年龄与卵巢反应性呈负相关,AFC与卵巢反应性成正相关。周期取消率为19.74%(30/152),卵巢低反应组(35.71%,10/28)明显高于非低反应组(16.13%,20/124)。移植周期临床妊娠率为51.64%(63/122),卵巢低反应组(22.22%,4/18)明显低于非低反应组(56.73%,59/104)。结论:年龄和AFC可用于卵巢低反应的预测。卵巢低反应可导致周期取消率升高、临床妊娠率降低。
Objective: To study the predictive value of ovarian low response and the pregnancy outcome under controlled hyperstimulation. Methods: Fifty-two infertile women who underwent IVF / ICSI assisted pregnancy were divided into two groups according to ovarian reactivity: low response group (<4 oocytes), non-low response group (oocytes≥4 One). Collecting infertile women’s relevant clinical data for analysis. Results: The incidence of ovarian low response was 18.42% (28/152). The two groups of age, basic FSH value, FSH / LH value, AFC significant difference. Multivariate logistic regression analysis showed that age and AFC entered the regression model, age was negatively correlated with ovarian response, and AFC was positively correlated with ovarian response. The rate of canceration was 19.74% (30/152), and the ovarian low response group (35.71%, 10/28) was significantly higher than the non-low response group (16.13%, 20/124). The clinical pregnancy rate was 51.64% (63/122) in the transplant cycle and 22.22% (4/18) in the ovary low response group (56.73%, 59/104). Conclusions: Age and AFC can be used to predict ovarian hyporesponse. Low ovarian response can lead to increased cycle cancellation rate, reduced clinical pregnancy rate.