Simultaneous determination of borneol and its metabolite in rat plasma by GC-MS and its application

• 作 者: Xiu-Man Sun Qiong-Feng Liao Yu
• 机 构: SchoolofChi,SchoolofPharmaceuticalSciences
• 出 处: 药物分析学报：英文版
• 发表日期: 2014年5期
• 关键词: WISTAR大鼠 GC-MS 药代动力学 天然冰片 代谢产物 同时测定 应用 血浆 Borneol Camphor Simultaneous determina
• 基金项目: supported by the National Natural Science Foundation of China (Nos. 81173564,81274028 and 81274102)

A gas chromatography mass spectrometry(GC-MS) method has been developed and fully validated for the simultaneous determination of natural borneol(NB) and its metabolite,camphor,in rat plasma.Following a single liquid-liquid extraction,the analytes were se