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本文应用同位素放射免疫方法对60例喉癌患者及26例正常人血清中癌胚抗原(CEA)进行检测。实验结果表明:喉癌患者血中癌胚抗原水平较正常人为高,P<0.01,具有显著性差异。对15例喉癌病人术前及术后癌胚抗原检测证明CEA水平在喉癌切除术后的患者下降至正常范围,但癌胚抗原水平与喉癌临床分期、分型无明显关系。实验结果提示喉癌患者血中癌胚抗原的检测,对喉癌的诊断有一定价值,并可以帮助判断治疗效果。
In this paper, 60 cases of laryngeal cancer patients and 26 normal human serum carcinoembryonic antigen (CEA) were detected by radioimmunoassay. The experimental results show that: the level of carcinoembryonic antigen in the blood of laryngeal cancer patients is higher than that in normal people, P <0.01, with significant difference. Preoperative and postoperative carcinoembryonic antigen test showed that CEA level decreased to the normal range after laryngectomy in 15 cases of laryngeal cancer patients. However, the level of CEA did not correlate with the clinical stage and classification of laryngeal cancer. The results suggest that the detection of carcinoembryonic antigen in laryngeal cancer patients has some value in the diagnosis of laryngeal cancer and can help determine the therapeutic effect.