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本文报告48例复发性脑转移瘤再手术结果。 男女各24例,年龄17～68岁(平均47.5岁)。原发灶类型:黑色素瘤14例,肺癌11例,乳腺癌10例,肾癌及结肠癌各4例,脊索瘤、生殖细胞瘤各1例,不明者3例。癌肿确诊至首次开颅平均间隔11.5月(0～109月),首次开颅时脑转移灶2个者5例,单发43例;术后全脑放疗31例。首次开颅术后至复发平均为6.7月(1.2～28.8月),复发时单个病灶42例,2个病灶6例;原位复发30例,远隔复发16例。二者均有2例;再手术前平均KPS评分(Karnof-sky performance scale)为80(40～100),有癌肿全身症状者23例。再手术前后4例无症状,有症状的44例术前及术后30天KPS评分比较,好转33例,稳
This article reports 48 cases of recurrent brain metastases re-operation results. 24 men and women of each age, aged 17 to 68 years (mean 47.5 years). Primary tumor types: melanoma in 14 cases, lung cancer in 11 cases, breast cancer in 10 cases, renal and colon cancer in 4 cases, chordoma, germ cell tumor in 1 case, unknown in 3 cases. The tumor was diagnosed until the first craniotomy average interval of 11.5 months (0 ~ 109 months), the first craniotomy two cases of brain metastases in 5 cases, single in 43 cases; postoperative brain irradiation in 31 cases. The average recurrence rate after the first craniotomy was 6.7 months (1.2-28.8 months). There were 42 cases of single lesions and 6 lesions of 2 lesions at the time of recurrence. There were 30 cases of recurrence in situ and 16 cases of distant recurrence. There were 2 cases in both groups. The Karnof-sky performance scale before reoperation was 80 (40-100), with 23 cases of systemic symptoms of cancer. Before and after reoperation, 4 asymptomatic and symptomatic 44 preoperative and postoperative 30 days KPS scores were compared, improvement in 33 cases, stable