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目的:对我院自制的15种内服制剂做了大肠杆菌的快速检定。方法:用MUGIndole(MI)法对制剂的大肠杆菌进行检定。结果:自然污染的15种制剂MI结果均为阴性;除复方莨菪片人工污染大肠杆菌的MI试验结果为阴性外,14种制剂的阳性对照管试验结果均显阳性。进一步对复方莨菪片的处方成分分别做了试验,其结果是,氨茶碱对人工污染大肠杆菌的MI试验结果显阴性;其它成分的MI结果均显阳性。结论:14种制剂对MI法均无影响;氨茶碱对本法有干扰。其原因有待进一步研究
OBJECTIVE: To rapidly test Escherichia coli in 15 kinds of oral preparations made by our hospital. Methods: MUG Indole (M I) method for the preparation of E. coli test. Results: The natural contamination of 15 kinds of preparations M I results were negative; in addition to compound scopolamine tablets artificial contamination of Escherichia coli M I test results were negative, the 14 preparations positive control tube test results were positive. Further tests on the prescription ingredients of compound scopolamine tablets were done, the result is aminophylline artificial contamination E. coli M I test results were negative; other components of the M I results were positive. Conclusion: There are 14 kinds of preparations have no effect on the M I; aminophylline interfere with this Act. The reason for further study