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目的:比较射频消融(RFA)辅助下前入路右半肝切除术与传统右半肝切除术治疗肝脏中部肿瘤的疗效及安全性。方法:将60例肝脏中部肿瘤患者按照随机数字法均分为对照组与观察组。对照组行传统右半肝切除术,观察组行RFA辅助下前入路右半肝切除术。比较两组手术情况、住院时间、并发症发生率与5年生存率等。结果:两组在手术时间差异无统计学意义(P>0.05),但观察组出血量、术中肿瘤破裂例数、术中大出血例数、输血例数及住院时间均明显少于对照组(均P<0.05);对照组总并发症发生率为46.67%,观察组为36.67%,两组差异无统计学意义(P>0.05);Kaplan-Meier分析显示对照组5年生存率43.09%,观察组为65.73%,两组差异有学意义(P<0.001)。结论:射频消融辅助下前入路右半肝切除术治疗肝脏中部肿瘤的效果显著,明显优于传统右半肝切除术。
Objective: To compare the efficacy and safety of radiofrequency ablation (RFA) -assisted anterior resection of the right hepatectomy with conventional right hepatectomy for the treatment of tumors in the middle of the liver. Methods: Sixty patients with central liver tumors were randomly divided into control group and observation group according to random number method. The control group received conventional right hepatectomy. The observation group underwent right anterior hepatectomy with RFA. The operation conditions, hospitalization time, complication rate and 5-year survival rate of the two groups were compared. Results: There was no significant difference in operative time between the two groups (P> 0.05). However, the amount of bleeding, the number of cases of tumor rupture, the number of cases of major bleeding, the number of transfusions and the length of hospital stay in the observation group were significantly less than those in the control group (P> 0.05). The incidence of total complication in the control group was 46.67% and in the observation group was 36.67%, with no significant difference between the two groups (P> 0.05). The Kaplan-Meier analysis showed that the 5-year survival rate was 43.09% The observation group was 65.73%, the difference between the two groups was significant (P <0.001). Conclusion: Radiofrequency ablation assisted anterior resection of the right hepatectomy for the treatment of tumors in the central liver was significantly better than the traditional right hemsection.