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化疗是非小细胞肺癌(non-small cell lungcancer,NSCLC)的主要治疗方法之一,在众多的化疗药物中,铂类药物的有效率已被大家所认可,但随着临床使用频率的增加,其耐药性亦逐渐显现。铂类药物耐药机制很复杂,其中核苷酸切除修复系统(nucleotide excision repair,NER)修复能力增强是耐药发生的主要原
Chemotherapy is one of the main treatments for non-small cell lung cancer (NSCLC). Among the many chemotherapeutic drugs, the efficiency of platinum drugs has been recognized by everyone, but with the increasing frequency of clinical use, chemotherapy Drug resistance is also gradually emerging. Platinum drug resistance mechanism is very complex, including nucleotide excision repair (nucleotide excision repair, NER) repair capacity is the main resistance to the original