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1983年3月至1996年2月间,在施行肿瘤细胞减灭术中,为62例因转移瘤侵犯深肌层或侵透肠腔的卵巢癌做了受侵肠段切除术。包括上皮性癌55例,恶性生殖细胞瘤4例,性索间质瘤3例。其中Ⅱ期1例,Ⅲ期39例,Ⅳ期2例,复发癌20例。术式主要为小肠部分切除、结肠部分切除及乙状结肠直肠部分切除术。术后给以顺铂为主的联合化疗。484%残余肿瘤小于2cm,2年及5年存活率为429%与16%,残余肿瘤小于2cm、化疗超过6个疗程者生存率高。结果提示:受侵肠段切除与化疗相结合能改善此类患者预后。
Between March 1983 and February 1996, in the course of tumor cytoreductive surgery, 62 cases of ovarian cancer due to metastatic tumor invading the deep muscle layer or invading the intestine cavity were subjected to an enterectomy. Including 55 cases of epithelial cancer, malignant germ cell tumor in 4 cases, 3 cases of sex stromal tumors. There were 1 case in phase II, 39 in stage III, 2 in stage IV, and 20 in recurrence. The surgical procedures consisted of partial resection of the small intestine, partial resection of the colon, and partial resection of the sigmoid colon. Cisplatin-based combination chemotherapy was given after surgery. 48.4% of the residual tumors were less than 2cm. The 2- and 5-year survival rates were 42.9% and 16%. The survival rate of residual tumors less than 2cm and chemotherapy over 6 courses was high. The results suggest that the combination of resection of the affected segment and chemotherapy can improve the prognosis of these patients.