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25年来,在心血管药理方面有明显的进展,一是一些新药相继问世;二是基于对危重病人的循环状态有进一步的了解,对新药和老药的应用更为合理。本文目的在于对循环衰竭治疗的现代概念的进展作一回顾。心泵功能取决于心室充盈压(前负荷),心肌收缩力及搏血阻力(后负荷)三大要素。这方面的知识随着重症医学的发展方才受到从事循环衰竭治疗医生们的重视。在50年代中,人们对循环衰竭的处理仅着眼于维持动脉压,为了尽可能保证脑、肾及
Over the past 25 years, there have been marked advances in cardiovascular pharmacology. The first is that some new drugs have come out in succession. The second is based on a better understanding of the circulatory state of critically ill patients and the more rational application of new and old drugs. The purpose of this paper is to review the progress made in the modern concept of treatment of circulatory failure. Cardiac pump function depends on ventricular filling pressure (pre-load), myocardial contractility and stroke resistance (after load) of the three elements. With the development of critical medicine, this knowledge has been taken seriously by physicians engaged in the treatment of circulatory failure. In the 1950s, people only focused on the treatment of circulatory failure to maintain arterial pressure. In order to ensure that the brain, kidney and