枣庄地区小儿支原体肺炎实验室检验结果及流行特点的研究

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目的对本地区肺炎支原体(MP)感染患儿实验室检验结果及流行特点进行研究分析,为制定有效防控策略及临床诊治提供依据。方法 185例呼吸道感染患儿,均进行肺炎支原体免疫球蛋白M(MP-IgM)检测,并对实验检查结果、发病年龄及季节分布进行分析研究。结果 185例呼吸道感染患儿,酶联免疫吸附试验(ELISA)检测结果 MP-IgM阳性36例,冷凝集试验结果 MP-IgM阳性25例,患儿多伴有多系统、多器官免疫损害,实验室检查异常。2~5岁年龄段MP-IgM阳性率50.0%高于其他年龄段;冬季MP-IgM阳性率47.2%高于其他季节。结论临床上对持续发热、顽固性咳嗽、病程长、普通抗生素治疗无改善的呼吸道感染患儿,依据年龄、季节分布特点,及早进行MP-IgM检测,以明确诊断、避免漏诊。 Objective To study and analyze the laboratory test results and epidemiological characteristics of children with Mycoplasma pneumoniae (MP) infection in this area in order to provide evidence for effective prevention and control strategies and clinical diagnosis and treatment. Methods A total of 185 children with respiratory tract infection were tested for mycoplasma pneumoniae immunoglobulin M (MP-IgM), and the results of the test, age of onset and season distribution were analyzed. Results 185 cases of respiratory tract infection in children, the results of enzyme-linked immunosorbent assay (MP-IgM) positive in 36 cases, cold agglutination test results MP-IgM positive in 25 cases, children with multiple systematic and multiple organ damage, the experimental Abnormal examination room. The positive rate of MP-IgM in 2 ~ 5 age group was 50.0% higher than other age groups; the positive rate of MP-IgM in winter was 47.2% higher than other seasons. Conclusion According to the characteristics of age and season, MP-IgM test should be conducted early to diagnose and avoid misdiagnosis in children with persistent respiratory infection, persistent cough, long course of disease and no improvement of general antibiotic therapy.
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