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资料来源于1994年1月～1996年8月连续完成的140例共580例次监测的原始记录。90%患者为口服,每日一次。血清地高辛含量(C_(DGX))检测采用TD_x(Abbott USA)及进口专用药盒,由专职检测员操作,保持误差<±6％。患者年龄≥50岁者120例,<50的成人7例(占11例次),小儿13例(占34例次)。男114例,女26例。老年病种以冠心病、心肌梗死、肺心病、心肌病和高心病为主,小儿以先心病和风心病为主。采样时患者所用剂最<0.125mg·d~(-1)共35例次(6%),0.125～0.375mg·d~(-1)共508例次(87.6％),0.5mg·d~(-1)共32例次(5.5%),>0.5gmg·d~(-1)共5例次(0.9%)。 结果:C_(DGX)分布<0.8 ng·ml~(-1)(0.56±0.15)者169例次(29.1%),0.8～2.0ng·ml~(-1)(1.26土0.33)者334例次
The data are from the original records of 580 cases monitored in succession from January 1994 to August 1996. 90% of patients are taken orally once daily. Serum digoxin level (C_ (DGX)) was detected by TD_x (Abbott USA) and imported special kit, and the error was <± 6%. There were 120 patients ≥50 years of age, 7 patients (<11 cases) <50 adults and 13 children (34 cases). There were 114 males and 26 females. Elderly patients with coronary heart disease, myocardial infarction, pulmonary heart disease, cardiomyopathy and high heart disease mainly in children with congenital heart disease and rheumatic heart disease. A total of 35 patients (6%), 0.125 ~ 0.375mg · d -1 (508.67%), 0.5mg · d ~ (-1) (-1), a total of 32 cases (5.5%),> 0.5gmg · d -1 (5 cases) (0.9%). Results: There were 334 cases (29.1%) with C_ (DGX) distribution of 0.8 ng · ml -1 (0.56 ± 0.15) and 0.8 ~ 2.0 ng · ml -1 (1.26 ± 0.33) Times