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目的观察二氧化碳(CO2)激光手术联合万乃洛韦口服治疗尖锐湿疣(CA)的临床疗效,并与单纯用CO2激光手术治疗CA进行了对比观察。方法将91例尖锐湿疣患者随机分成两组。治疗组:50例患者采用二氧化碳(CO2)激光手术联合万乃洛韦口服治疗;对照组:41例采用单纯CO2激光治疗,对两组临床疗效进行对比分析。结果治疗组临床疗效明显优于对照组,治疗组总有效率为88.0%,对照组总有效率为29.3%,两组比较差异有非常显著性意义(P<0.01)。结论激光手术联合万乃洛韦口服治疗尖锐湿疣具有临床疗效好、副作用较少、复发率较低的作用。
Objective To observe the clinical efficacy of carbon dioxide (CO2) laser combined with valacyclovir in the treatment of condyloma acuminatum (CA), and to observe the effect of CO2 laser surgery alone on CA. Methods 91 cases of genital warts were randomly divided into two groups. In the treatment group, 50 patients were treated with carbon dioxide (CO2) laser combined with valacyclovir. In the control group, 41 patients were treated with CO2 laser only. The clinical efficacy of the two groups were compared. Results The clinical efficacy of the treatment group was significantly better than that of the control group. The total effective rate was 88.0% in the treatment group and 29.3% in the control group. There was significant difference between the two groups (P <0.01). Conclusion Laser surgery combined with valalovlovine for the treatment of condyloma acuminatum has good curative effect, less side effects and lower recurrence rate.