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目的 :探讨药物对高原低氧条件下负荷运动后人体光觉功能的影响。方法 :选择驻守海拔 370 0m6个月的汉族男性青年 2 0人 ,分甲、乙两组分别口服酪氨酸与乙酰唑胺。于服药前、服药15天和停药 10天三个阶段时采用EGM型脚踏车功量仪进行达负荷指标的运动 (负荷指标 :W 2 2 5 ,P 175～ 180次 分 ) ,于每次运动后 15分钟 ,应用暗房夜光表测验法[1] ,检测观察暗适应反应时间。结果 :海拔 370 0m服药前运动前、暗适应反应时间显著长于平原人 (P <0 .0 1)。服药前运动后暗适应时间显著长于服药前运动前 (P <0 .0 1) ;停药 15d运动后暗适应时间显著短于服药前运动前、后与停药 10d运动后 (P <0 .0 1)。停药 10天运动后与服药前运动后比较暗适应反应时间显著缩短 (P <0 .0 1)。与服药前运动前比较无显著性差异 (P >0 .0 5 )。结论 :酪氨酸与乙酰唑胺均能有效的改善和提高高原低氧条件下负荷运动前后人体光觉功能
Objective: To investigate the effect of drugs on the photoreceptor function of human body after load exercise under the condition of plateau hypoxia. Methods: A total of 20 Han male youths were enrolled at an altitude of 370 m and an average of 6 months. A group of tyrosine and acetazolamide was orally administered to two groups. Before loading, taking medicine for 15 days and stopping for 10 days, the EGM-type bicycle dynamometer was used to carry out the load index exercise (load index: W 2 2 5, P 175 ~ 180) in each exercise After 15 minutes, the application of dark room luminous table test [1], the test observed dark adaptation reaction time. Results: Before exercise at an elevation of 370 0m, dark adaptation reaction time was significantly longer than that of plain people (P <0.01). The time of dark adaptation after exercise was significantly longer than that before medication (P <0.01). The time of dark adaptation after stopping 15 days of exercise was significantly shorter than that before exercise and after 10 days of exercise (P <0. 0 1). After 10 days of withdrawal from exercise and before exercise, the dark adaptation reaction time was significantly shortened (P <0.01). There was no significant difference compared with before exercise (P> 0.05). CONCLUSION: Both tyrosine and acetazolamide can effectively improve and enhance the body’s light perception before and after exercise under plateau hypoxia