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糖尿病的诊断和治疗过程中,仅以血糖和尿糖水平作为监测手段是不够的,因为血糖主要代表瞬间体内血糖水平。1983年 Johnson[Clin chim Acta1983;128:87]提出血清果糖胺测定可以了解病人一个时期控制状态(过去一个月左右)。我们采用该法对糖尿病人进行了监测,结果报告如下。对象和方法健康对照组60例(男31例,女29例),我市中心血站献血员,无糖尿病史,血糖和尿糖检测阴性,年龄25～50岁。糖尿病患者72例(男33例,女39例),为门诊及住院糖尿病人,年龄28～65岁。受试者于清晨空腹采血2ml,分别测定血糖和果糖胺,空腹血糖采用葡萄糖氧化酶法,果糖胺采用上海化学试剂研究所生产的试剂盒,严格按试剂说明书进行。结果60例健康对照组果糖胺水平2.23±0.38mmol/L。72例糖尿病组果糖胺水平为3.48±
In the diagnosis and treatment of diabetes, the mere use of blood glucose and urine glucose levels as a means of monitoring is not sufficient, as blood glucose mainly represents instantaneous in vivo blood glucose levels. In 1983, Johnson [Clinchim Acta 1983; 128: 87] suggested that serum fructosamine assay could be used to understand a patient’s state of control over the past month or so. We use this method for monitoring of diabetes, the results are reported as follows. Subjects and Methods Healthy control group of 60 patients (31 males and 29 females), blood donors in our downtown blood donors, no history of diabetes, blood glucose and urine sugar negative, aged 25 to 50 years. 72 cases of diabetic patients (33 males and 39 females), outpatients and inpatients with diabetes, aged 28 to 65 years. Subjects fasting in the morning blood 2ml, respectively, determination of blood glucose and fructosamine, fasting glucose using glucose oxidase method, fructosamine using Shanghai Institute of Chemical Reagents produced kits, in strict accordance with reagent instructions. Results The 60 cases of healthy control group of fructosamine level of 2.23 ± 0.38mmol / L. The fructosamine level in 72 diabetic patients was 3.48 ±