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近年来,白喉发病有向大年龄组推移的趋势,而大年龄组儿童及成人全量接种白喉类毒素反应大,不能使用。为探讨防止白喉流行区大年龄组儿童和成人发病的有效方法,我站于1977年11月24日至12月30日,在近几年白喉发病较高的金斗公社对1,715人进行了锡克氏试验,对其中342人阳性者进行了吸附精制白喉类毒素(简称吸精白类)小剂量皮内注射,观察免疫接种后的反应,考核免疫效果。材料与方法一、材料: 1.吸精白类:成都生物制品研究所出品。 2.锡克氏毒素液和对照液:上海生物制品研究所
In recent years, the incidence of diphtheria has the tendency to shift to the older age group, while the full-dose diphtheria toxoid in children and adults in the older age group has a large response and can not be used. In order to explore an effective way to prevent the onset of the disease in children and adults of the older age group in the prevalence area of diphtheria, from November 24, 1977 to December 30, 1977, 1,715 people at Tin King Commune, which had a high incidence of diphtheria, Kirschner test, of which 342 were positive for purified diphtheria toxoid (referred to as white extract) low-dose intradermal injection, observe the response after immunization to assess the immune effect. Materials and methods First, the material: 1. Suction white: Chengdu Institute of Biological Products produced. 2. Sick’s toxin solution and control solution: Shanghai Institute of Biological Products