论文部分内容阅读
目的探讨血清IgA、C3水平及IgA/C3比值在原发性IgA肾病中的临床意义.方法以透射免疫比浊法测定69例经肾穿刺活检确诊为原发性IgA肾病患者和58例非IgA原发性肾小球肾炎患者血清IgA及C3水平,按Haas分级标准评估IgA肾病的病理分型,同时对结果进行分析.结果原发性IgA肾病患者与非IgA原发性肾小球肾炎患者血清IgA水平分别为[(3.01±0.91)vs(2.51±1.05)g/L,P0.05];IgA/C3比值分别为(3.05±1.03 vs 3.31±1.45,P>0.05).结论血清IgA、C3水平及IgA/C3比值可作为鉴别原发性IgA肾病与非IgA肾病的参考指标.“,”Objective To analyze the difference of serum IgA,C3 levels and IgA/ C3 ratio between the patients with primary IgA nephropathy(IgAN) and non-IgA nephropathy and observe the correlation of these parameters with Haas’s grading system in patients with IgA nephropathy.Methods 69 patients with primary IgA nephropathy and 58 patients with non-IgA nephropathy were diagnosed by renal biopsy,the levels of serum IgA,C3 were detected with turbidimetric method in all patients.Patho-grading was evaluated according to the standard of Haas grading.Results The levels of serum IgA in the patients with IgAN were significantly higher than those in patients with non-IgA nephropathy(3.01±0.91 vs 2.51±1.05g/L,P0.05) and IgA/ C3 ratio(3.05±1.03 vs 3.31±1.45,P>0.05) of the patients with class Ⅲ,Ⅳ,Ⅴ was higher than classⅠand Ⅱ,but the differences between groups was not statistically significant.Conclusion The serum IgA,C3 levels and IgA/ C3 ratio could be used as reference parameter to identify primary IgA nephropathy from non-IgA nephropathy.