论文部分内容阅读
目的 :了解广东沿海地区吸毒人群中海洛因海绵状白质脑病的流行病学特点。方法 :采用整群抽样对广东沿海地区六市 1 8个戒毒所中 44 2 8名吸毒人员进行神经系统检查 ,发现异常者即查头颅核磁共振 ,凡有共济失调、头颅核磁共振示大脑或小脑对称性脱髓鞘改变者纳入调查对象。结果 :44 2 8名吸毒人群中发现了 1 4例海洛因海绵状白质脑病 ,总体发病率为 0 .3 2 % ;潮阳、河源两地发病率较高 ;其发病与吸毒方式有关。结论 :海洛因海绵状白质脑病在世界上报道不多 ,此次在我国由我们首次发现。该病仅见于经鼻烫吸患者 ,呈地区性小规模流行性发病 ,提示该病可能是由一种未明毒物引起的特殊类型的中毒性脑病 ,该毒物在吸毒者烫吸过程中产生 ,可能来源于某批毒品的添加剂
OBJECTIVE: To understand the epidemiological characteristics of heroin cavernous leukoencephalopathy among drug users in the coastal areas of Guangdong. Methods: A total of 44 28 drug addicts in 18 detoxification centers in 6 cities in Guangdong coastal area were examined by cluster sampling. The abnormalities were examined by cranial magnetic resonance imaging (MRI) Cerebellar symmetry demyelination were included in the survey. Results: Forty-four drug abusers found 14 cases of spontaneous herpes leukoencephalopathy, the overall incidence was 0.32%. The incidence of Chaoyang and Heyuan were higher. The incidence was related to the mode of drug abuse. Conclusion: Heroin has been reported in the world for the first time in our country. The disease is seen only in patients with rhinosinusitis and presents with a small-scale endemic epidemic suggesting that the disease may be a specific type of toxic encephalopathy caused by an unspecified poison, From a batch of drugs additives