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目的 评价TP、NP、IEP方案 治疗晚期非小细胞肺癌的有效率和中位生存期。方法 1997年1月～1999年3月应用TP(紫杉醇、顺铂)及NP(诺维本、顺铂)、IEP(异环磷酰胺、足叶乙甙、顺铂)方案治疗94例晚期非小细胞肺癌。结果 三组有效率分别为TP组51.8％,NP组46.6％,IEP组43.2％。三组中位生存期分别为TP组9.3个月,NP组8.9个月,IEP组8.2个月。结论 TP组、NP组、IEP组治疗晚期非小细胞肺癌有效率相近(P>0.05),中位生存期无明显差异。
Objective To evaluate the efficacy and median survival of TP, NP and IEP regimens in the treatment of advanced non-small cell lung cancer. Methods From January 1997 to March 1999, TP (paclitaxel, cisplatin), NP (Novobine, Cisplatin), IEP (ifosfamide, etoposide, cisplatin) regimens were used to treat 94 cases of advanced non- Small Cell Lung Cancer. Results The effective rates of the three groups were 51.8% in the TP group, 46.6% in the NP group, and 43.2% in the IEP group. The median survival time for the three groups was 9.3 months in the TP group, 8.9 months in the NP group, and 8.2 months in the IEP group. Conclusions The TP group, NP group, and IEP group have similar efficacy in the treatment of advanced non-small cell lung cancer (P>0.05). There is no significant difference in the median survival period.