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急性胰腺炎的诊断通常是根据特有的临床表现及血浆淀粉酶值超出正常范围均数10个标准差来作出的。虽然血浆脂酶的升高是急性胰腺炎出现时更为灵敏和特异的指标,但由于其测定方法繁琐和有时不可靠,过去一直未采用这一测定。少数伴有昏迷、休克、黄疸、肾功能不全及呼吸窘迫等器官功能衰竭表现的急性胰腺炎病人,入院时很可能没有考虑到胰腺炎,从而忽略了酶的检查,常导致误诊。虽然难以对所有急症病人常规测定淀粉酶或脂酶,但一个简单筛选测定可以提示酶水平的升高或正常。为此作者报道一个试点研究,即做凝集试验,以筛选脂酶水平高于300μg/l(正常8～52μg/l)的患者,任何一个医务人员
Diagnosis of acute pancreatitis is usually based on the specific clinical manifestations and plasma amylase value beyond the normal range of 10 standard deviations to make. Although elevated plasma lipase is a more sensitive and specific indicator of acute pancreatitis, this assay has not been used in the past because of its cumbersome and sometimes unreliable assay. A small number of patients with acute pancreatitis associated with organ failure such as coma, shock, jaundice, renal insufficiency, and respiratory distress may not have taken pancreatitis into account at the time of admission, neglecting enzyme tests and often misdiagnosing. Although it is difficult to routinely determine amylase or lipase for all acute patients, a simple screening assay can indicate elevated or normal enzyme levels. To this end, the authors report on a pilot study, an agglutination test, to screen patients with lipase levels above 300 μg / l (normal 8 to 52 μg / l), any medical staff