论文部分内容阅读
目的研究沐舒坦用于治疗新生儿胎粪吸入综合征的效果。方法 80例胎粪吸入综合征新生儿作为观察对象,根据随机数字表法分为观察组与对照组,各40例。两组患儿均采用常规对症治疗,观察组患儿加用沐舒坦治疗,对比分析两组患儿的呼吸机使用时间、住院时间、血氧分压(PaO_2)、血二氧化碳分压(PaCO_2)及临床疗效等。结果观察组患儿治疗总有效率为87.5%,明显高于对照组的67.5%,差异具有统计学意义(P<0.05)。观察组患儿呼吸机使用时间(58.5±11.4)h及住院时间(129.2±23.5)h均明显短于对照组(72.1±12.5)h、(167.9±26.4)h,差异均具有统计学意义(P<0.05)。治疗前两组患儿PaO_2及PaCO_2水平对比差异无统计学意义(P>0.05);治疗后6 h,与对照组患儿对比,观察组PaO_2更高,PaCO_2更低,差异均具有统计学意义(P<0.05)。结论在新生儿胎粪吸入综合征的治疗中采用沐舒坦治疗有助于促进患儿的早日康复,缩短治疗疗程,改善患儿的通气状况,值得在临床治疗中推广应用。
Objective To study the effect of mucosolvan in the treatment of neonatal meconium aspiration syndrome. Methods Eighty newtons with meconium aspiration syndrome were divided into observation group and control group according to random number table method, 40 cases in each group. The patients in both groups were treated with routine symptomatic treatment. The patients in the observation group were treated with mucosolvan. The duration of ventilator, length of hospital stay, partial pressure of oxygen (PaO_2) and partial pressure of carbon dioxide (PaCO_2) And clinical efficacy. Results The total effective rate of observation group was 87.5%, significantly higher than 67.5% of control group, the difference was statistically significant (P <0.05). The use of ventilator in the observation group (58.5 ± 11.4 h) and hospital stay (129.2 ± 23.5 h) were significantly shorter than those in the control group (72.1 ± 12.5 h) and (167.9 ± 26.4 h), respectively P <0.05). There was no significant difference in the PaO_2 and PaCO_2 levels between the two groups before treatment (P> 0.05). Compared with the control group, PaO_2 and PaCO_2 were lower in the observation group 6 h after treatment, the differences were statistically significant (P <0.05). Conclusions Mucosolvan in the treatment of neonatal meconium aspiration syndrome can promote the early recovery of children, shorten the course of treatment and improve the ventilation of children. It is worth to be popularized and applied in clinical treatment.