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目的:观察早期声带癌患者CO2激光手术后应用普米克令舒雾化吸入治疗的临床效果。方法:将CO2激光喉早期声带癌显微手术后患者120例随机分成2组,其中实验组60例应用普米克令舒雾化吸入,每日2次,每次1 mg;对照组60例采用地塞米松5 mg,庆大霉素8万u,糜蛋白酶4000u日2次混合雾化吸入,同时使用7天,对比2组术后呼吸困难、粘膜水肿、发热、声嘶、疼痛等发生情况效果。结果:实验组的患者,术后愈复天数、呼吸困难及咳嗽发生率明显低于对照组,差异有显著性意义(P<0.05),而术后发热情况及声音嘶哑情况二者无明显差异(P>0.05)。结论:普米克令舒雾化吸入能有效缩短喉CO2激光显微外科手术患者的痊愈时间。
Objective: To observe the clinical effect of pulmicort respirator inhalation after CO2 laser surgery in patients with early stage of vocal cord cancer. Methods: 120 patients with early postoperative CO2 laser laryngeal vocal cord cancer microsurgery were randomly divided into 2 groups, of which 60 patients in the experimental group were treated with Pulmicort Respiratory inhalation 2 times a day for 1 mg each, and 60 in the control group Dexamethasone 5 mg, gentamicin 80 000 u, chymotrypsin 4000 u day 2 times mixed inhalation, while using 7 days, compared two groups of postoperative dyspnea, mucosal edema, fever, hoarseness, pain, etc. effect. Results: The experimental group patients, the number of days after recovery, the incidence of dyspnea and cough were significantly lower than the control group, the difference was significant (P <0.05), while there was no significant difference between postoperative fever and hoarseness (P> 0.05). Conclusion: Pulmicort respiration inhalation can effectively shorten the recovery time of laryngeal CO2 laser microsurgery.