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目的监测江苏省2009～2011年间流感病例,掌握季节性流感优势毒株的变化及流行特征,为流感防制提供科学依据。方法搜集2009年1月～2011年12月间14家流感监测网络实验室所接受的流感样病例(Influenza-like Ill-ness,ILI)监测信息,如病例信息、病毒核酸分离和检测,并对数据进行统计分析。结果共受理标本69774例,核酸阳性标本约占19.7%;不同性别ILI的核酸检出阳性率没有统计学差异,不同年龄组、实验室和月份组ILI的阳性检出率存在统计学差异:10～30岁年龄组ILI的阳性检出率相对较高,常州市疾控中心的ILI检出率相对较高,9月份至第二年4月份间为阳性率高峰期。季节性H3N2、新甲型H1N1和B型的顺序交替成为江苏省2009年6月～2011年6月间的优势毒株,B型流感成为2011年4月后唯一的流行毒株。结论在流感病毒检出率较高的年龄组、地区和月份,如10～30岁等,应加强流感的预防控制;在季节性H3N2、新甲型H1N1和B型流感的流行季节制定疫苗接种等有效措施,以减少流感流行造成的疾病负担。
Objective To monitor the cases of influenza in Jiangsu Province from 2009 to 2011 and to master the changes and epidemic characteristics of the predominant strains of seasonal influenza and provide a scientific basis for the prevention and control of influenza. Methods Influenza-like Ill-nees (ILI) monitoring data were collected from 14 influenza surveillance network laboratories from January 2009 to December 2011, such as case information, viral nucleic acid isolation and detection Data for statistical analysis. RESULTS: A total of 69774 specimens were accepted and about 19.7% of them were positive for nucleic acid. The positive rates of ILI in different sexes were not statistically different. The positive rates of ILI in different age groups, laboratories and months were statistically different: 10 The positive detection rate of ILI in the age group of ~ 30 years old is relatively high. The detection rate of ILI in Changzhou CDC is relatively high, and the peak rate of positive rate is from September to April of the next year. The sequence of seasonal H3N2, new H1N1 and type B alternated to become the dominant strain in Jiangsu Province from June 2009 to June 2011, and influenza B became the only pandemic strain after April 2011. Conclusion The prevention and control of influenza should be strengthened in the age groups, regions and months with high detection rate of influenza virus, such as 10-30 years old. Vaccination should be made in the seasonal season of H3N2, new H1N1 and influenza B And other effective measures to reduce the burden of disease caused by the epidemic.