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研究抗心磷脂抗体(aCL)水平与缺血性脑血管病(ICVD)的关系.ELISA定量检测266例ICVD患者血清aCL,并与147例健康者对照.结果:ICVD组aCL阳性率为23.3%,对照组为4.76%,前者明显高于对照组(P<0.01),且IgG型aCL比IgM型aCL阳性率明显升高(P<0.01),提示aCL(特别是IgG型)与 ICVD密切相关.aCL≥10GPL或MPL的ICVD患者发病年龄轻且易复发.提示:对于年轻、有反复发作史和原因不清的ICVD患者检测aCL是必要的,aCL升高可作为ICVD危险性增加的指标.
To investigate the relationship between anti-cardiolipin antibody (aCL) and ischemic cerebrovascular disease (ICVD). ELISA was used to detect serum aCL in 266 ICVD patients and to 147 healthy controls.Results: The positive rate of aCL in ICVD was 23.3% , The former was significantly higher than that of the control group (P <0.01), and the positive rate of aCL was higher than that of IgM (P <0.01), suggesting that aCL (especially IgG type) is closely related to ICVD ICVD patients with .aCL ≥10 GPL or MPL are young and relapsed, suggesting that aCL is necessary for the detection of aCL in young, recurrent and unexplained ICVD patients and elevated aCL may be used as an indication of increased ICVD risk.