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本文主要是对环磷酰胺引起缓解期的微小病变型肾病患者的抑制性T细胞功能长期损害后使患者不致复发的报告。并表明抑制性T细胞对微小病变型肾病有致病作用。发现环磷酰肢使微小病变型肾病不复发是因为使抑制性T细胞的功能减退。本文经组织学诊断的微小病变型肾病的31例患者,均处于缓解期、无蛋白尿、血白蛋白水平和肾功能均正常。病人分为两组: 环磷酰胺治疗组21例,平均年龄32.1岁,平均缓
This article is mainly for cyclophosphamide in patients with minimal change of renal disease caused by inhibition of T-cell function long-term damage after the patient does not cause recurrence report. And showed that suppressive T cells have a pathogenic role in minimal change nephropathy. It was found that cyclophosphamide does not relapse to minimal change nephropathy because of diminished function of suppressor T cells. The histological diagnosis of minimal change in patients with nephropathy in 31 patients, were in remission, no proteinuria, serum albumin levels and renal function were normal. Patients were divided into two groups: 21 cases of cyclophosphamide treatment group, the average age of 32.1 years, the average slow