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本文报告采用氯霉素试验组和对照组动物实验研究方法,发现试验组小鼠白细胞总数用药后明显低于正常(P<0.01) 而对照组小鼠白细胞总数用药后无变化(P>0.05)停药后二周试验组小鼠白细胞总数恢复正常水平(P>0.05),分析结果氯霉素对小鼠白细胞生成抑制的可逆性。
In this paper, we report the use of the chloramphenicol test group and the control group animal experimental study method and found that the total number of white blood cells in the experimental group was significantly lower than normal after treatment (P<0.01), but the total number of white blood cells in the control group mice did not change after treatment (P>0.05) The total number of white blood cells returned to normal in the experimental group two weeks after drug withdrawal (P>0.05). The results showed that the inhibition of leukocyte production by chloramphenicol was reversible.