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本文报告2例子宫内膜异位症经腹全子宫和双附件切除术后,用外源性雌激素替代治疗后静止的病灶发生恶变。例1,63岁,未产,白人妇女,1969年(49岁)时因多发性肌瘤和广泛子宫内膜异位症无恶性证据行全子宫双附件切除术,术后给予结合雌素治疗。1981年9月患者发生阴道出血和左胁腹部痛,经静脉肾盂造影证明左输尿管近膀胱3cm 处梗阻。1981年11月开腹探查发现肿瘤复盖左输尿管,并与膀胱粘连,病检诊断为子宫内膜异位症伴宫内膜样癌变。1981年12月1日行残余病灶切除和部分膀胱切除,
This article reports 2 cases of endometriosis abdominal total hysterectomy and double attachment resection, with exogenous estrogen replacement therapy after the static lesions of malignant transformation. Cases 1,63 years old, unproductive, white women, 1969 (49 years) due to multiple fibroids and extensive endometriosis no evidence of malignancy double uterine hysterectomy, postoperative combined with estrogen therapy . September 1981 patients with vaginal bleeding and left flank abdominal pain, confirmed by intravenous pyelography 3cm near the left ureter at the obstruction. Open exploration in November 1981 found that the tumor covered the left ureter, and bladder adhesions, disease diagnosis of endometriosis with endometrial cancer. December 1, 1981 line residual tumor resection and partial cystectomy,