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慢性血栓栓塞性肺动脉高压(chronic thromboembolic pulmonary hypertension,CTEPH)是导致严重肺动脉高压(pulmonary artery hypertension,PAH)的主要原因之一。CTEPH在临床上并不少见,但由于认识不足,常延误诊断和治疗,致使患者死亡。CTEPH是由于肺动脉被未完全及机化的血栓阻塞,继而引起肺动脉阻力增加。该病发病率有逐年上升趋势。在无干预状态下,CTEPH无有效的内科治疗方法,肺动脉内膜剥脱术(pulmonary thromboendarterctomy,PTE)是较好的可选择的外科治疗手段。肺移植术仅是PTE不可行时的替代性治疗。
Chronic thromboembolic pulmonary hypertension (CTEPH) is one of the major causes of severe pulmonary artery hypertension (PAH). CTEPH is not uncommon in clinical practice, but due to lack of understanding, it is often delayed diagnosis and treatment, resulting in death of patients. CTEPH is due to incomplete and mechanical pulmonary embolism blocked thrombus, which in turn leads to increased pulmonary artery resistance. The incidence of the disease has increased year by year. In the absence of intervention, CTEPH no effective medical treatment, pulmonary arterial remodeling (pulmonary thromboendarterctomy, PTE) is a better alternative surgical treatment. Lung transplantation is only an alternative treatment when PTE is not feasible.