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目的 探讨胸腔内灌注大剂量高聚金葡素治疗恶性胸水的疗效。方法 32例由组织学或/和细胞学诊断的恶性胸腔积液,经针吸或置管排液后注入大剂量高聚金葡素2×10~4单位(40ml)进行治疗。结果 CR11例、PR16例、NC5例,有效缓解率84.4％(27/32)。毒副反应:高热21例(65.6％)。疼痛12例(37.5％),经对症处理可缓解。结论 与其他胸水治疗方法比较,该方法具有疗效高、毒副反应低的特点。
Objective To investigate the efficacy of intrapleural infusion of high-dose hyperglycemia in the treatment of malignant pleural effusion. Methods Thirty-two cases of malignant pleural effusions diagnosed by histology or/and cytology were treated by needle aspiration or catheter drainage followed by infusion of 2×10 4 units (40 ml) of high-dose staphylococcus aureus. Results There were 11 cases of CR, 16 cases of PR, and 5 cases of NC5. The effective remission rate was 84.4% (27/32). Toxic side effects: High fever in 21 cases (65.6%). Pain in 12 cases (37.5%) was relieved by symptomatic treatment. Conclusion Compared with other pleural fluid therapy methods, this method has the characteristics of high efficacy and low toxicity.