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报告1例由于头皮撕裂伤感染肉毒杆菌引起的创伤性肉毒中毒,伤后11天出现全身无力、视物模糊、上睑下垂、咽下困难、呼吸肌麻痹等肉毒中毒的临床症状。伤口分泌物检出A型肉毒毒素和肉毒杆菌,血清中也检出A型肉毒毒素。经用肉毒抗毒素、人工呼吸机和创口局部积极治疗,挽救了病人的生命。结合复习文献,讨论本病的诊断要点、治疗原则和预防措施,并指出本例可能系颅脑损伤并发肉毒中毒的首例报告。
One case of traumatic botulism caused by botulism was reported due to scalp laceration, clinical manifestations of botulism such as generalized weakness, blurred vision, ptosis, dysphagia, and respiratory muscle paralysis were observed 11 days after injury . Wound secretions detected botulinum toxin type A and botulinum toxin type A, botulinum toxin type A was also detected in the serum. The use of botulinum antitoxin, respirators and wounds in the local active treatment, saved the patient’s life. Combined with the review of the literature to discuss the diagnosis of the disease points, principles of treatment and preventive measures, and pointed out that this case may be the first case of brain injury complicated with botulism.