Expression and Significance of MicroRNA-21 and P-gp in Colon Cancer Cells

• 作 者: Xiaoli YAN Yanfang FAN Peng YA
• 机 构: ChengdeMedicalUniversity
• 出 处: 药用植物研究:英文版
• 发表日期: 2020年2期
• 关键词: COLORECTAL CANCER MIR-21 ABCB1 P-GP
• 基金项目: Provincial-level Project of Hebei of Priority Discipline Construction(031412),School-level Natural Fund Project of Chengde Medical University(201830).

[Objectives]To investigate the expression and significance of miR-21 and P-gp in colon cancer cell line HCT-15.[Methods]RT-qPCR was used to detect the miR-21 and ABCB1 mRNA expression level of P-gp coding genes in normal colon mucosal cell NCM460 and colo